Director, Media Strategy and Execution

• Lead portfolio-level media strategy across the U.S. Metabolic Conditions Business Unit, including 5 disease states, plus any additional as the business unit grows. • Partner with media agency to develop annual, quarterly, and in-cycle media plans that translate brand strategies, audience insights, market dynamics, and business objectives into clear media priorities, channel roles, tactical recommendations, and investment plans. • Partner with brand teams to define what media must accomplish for each brand, including awareness, education, diagnosis, treatment consideration, patient finding, switching, retention, adherence, and customer engagement objectives. • Drive integrated HCP and patient/caregiver media planning across channels such as paid search, paid social, programmatic, endemic and non-endemic media, video/CTV, digital partnerships, emerging platforms, and other priority media opportunities. • Ensure media plans are grounded in rare disease audience realities, including small patient populations, high-intent moments, complex treatment journeys, HCP specialty dynamics, caregiver roles, and compliant use of data and targeting capabilities. • Lead media budget planning, allocation, scenario development, and funding tradeoff recommendations across brands, audiences, campaigns, and vendors. • Oversee agency partners across media strategy, planning, buying, trafficking, tagging, optimization, reporting, innovation, and budget stewardship, holding partners accountable for quality, efficiency, transparency, timelines, and measurable impact. • Partner with Procurement, Finance, Commercial Operations, and brand teams to improve working/non-working media efficiency, strengthen scope discipline, and ensure media fees, pass-throughs, invoices, accruals, and reconciliations are managed appropriately. • Establish consistent planning principles, operating rhythms, decision forums, documentation standards, and performance review processes across the portfolio while allowing for brand-specific needs and market conditions. • Collaborate with internal teams, including Brand Marketing, Digital & Analytics, Business Operations, CRM, Privacy, and Compliance stakeholders to ensure media plans are integrated with omnichannel roadmaps and customer engagement capabilities. • Define measurement frameworks, KPIs, dashboards, reporting inputs, and learning agendas in partnership with agency, analytics and digital teams, ensuring measurement goes beyond activity metrics to as

• Bachelor’s degree or equivalent combination of education and relevant experience. • At least ten years of experience in media strategy, media planning, digital marketing, omnichannel engagement or related commercial disciplines. • Direct experience working at a media agency, including media planning, buying, trafficking, tagging, optimization, or reporting deliverables. • Demonstrated ability to develop integrated HCP and patient/caregiver media strategies that connect audience insight, channel strategy, content needs, activation plans, measurement, and optimization. • Strong knowledge of digital media channels and planning principles, including paid search, paid social, programmatic, video/CTV, endemic media, non-endemic media, digital partnerships, CRM-connected journeys, and emerging media models. • Experience managing media budgets, agency partners, vendor relationships, media authorizations, scope discussions, reporting, and investment tradeoffs. • Experience using campaign reporting, dashboards, test results, audience quality indicators, web analytics, and other performance data to develop practical business recommendations. • Understanding of U.S. pharmaceutical marketing dynamics, including HCP engagement, patient and caregiver journeys, promotional review requirements, privacy considerations, and compliant use of data. • Strong strategic thinking, analytical orientation, financial acumen, communication skills, and ability to influence senior stakeholders in a matrixed environment. • Excellent organizational skills and ability to manage multiple brands, priorities, timelines, partners, and decision processes with disciplined follow-through.

Who We Are BioMarin is a leading rare disease biotechnology company focused on genetically defined conditions. Guided by our purpose to develop medicines that make a profound impact on people’s lives, our global teams have delivered a portfolio of therapies since our founding in 1997. Our revolutionary treatments for conditions like achondroplasia (the most common form of dwarfism), PKU (phenylketonuria), CLN2, a form of Batten disease, and a number of forms of MPS (mucopolysaccharidosis) offer new possibilities for patients and families who previously had few, if any, available options. More recently, with the close of the Amicus acquisition, our portfolio has expanded to include therapies for Fabry disease and Pompe disease, expanding our ability to reach more people living with rare genetic conditions. Our success comes from our unwavering commitment to excellence, our deep understanding of patient needs, our scientific expertise, and our world-class manufacturing capabilities. At the heart of BioMarin is a dedicated team of the brightest minds in the industry working together to deliver innovative therapies to patients and families around the world. About Commercial Be part of the worldwide infrastructure that gets our drugs to underserved patients around the world. Our global sales force solidifies BioMarin’s commercial presence in the United States and Europe and is rapidly growing in other regions, such as South America, EuMEA, and Asia-Pacific. Role Summary The Director, Media Strategy and Execution will lead the development and execution of media plans that support brand ambitions across BioMarin’s Metabolic Conditions Business Unit. This role will centralize media expertise across a complex rare disease portfolio, ensuring media strategy, investment, activation, optimization, and measurement are tightly connected to brand objectives, patient and HCP audience needs, business priorities, and performance outcomes. The Director will serve as a strategic partner to brand teams, agencies and cross-functional leaders, bringing discipline, innovation, and accountability to how BioMarin plans and activates paid media across HCP, patient, caregiver, and related healthcare audiences. The successful candidate will combine rare disease marketing judgment, strong media fluency, agency leadership, financial discipline, and the ability to translate data into clear decisions that improve customer engagement and business impact. This role will report directly to the Head of Marketing, US Metabolic Conditions. Key Responsibilities • Lead portfolio-level media strategy across the U.S. Metabolic Conditions Business Unit, including 5 disease states, plus any additional as the business unit grows. • Partner with media agency to develop annual, quarterly, and in-cycle media plans that translate brand strategies, audience insights, market dynamics, and business objectives into clear media priorities, channel roles, tactical recommendations, and investment plans. • Partner with brand teams to define what media must accomplish for each brand, including awareness, education, diagnosis, treatment consideration, patient finding, switching, retention, adherence, and customer engagement objectives. • Drive integrated HCP and patient/caregiver media planning across channels such as paid search, paid social, programmatic, endemic and non-endemic media, video/CTV, digital partnerships, emerging platforms, and other priority media opportunities. • Ensure media plans are grounded in rare disease audience realities, including small patient populations, high-intent moments, complex treatment journeys, HCP specialty dynamics, caregiver roles, and compliant use of data and targeting capabilities. • Lead media budget planning, allocation, scenario development, and funding tradeoff recommendations across brands, audiences, campaigns, and vendors. • Oversee agency partners across media strategy, planning, buying, trafficking, tagging, optimization, reporting, innovation, and budget stewardship, holding partners accountable for quality, efficiency, transparency, timelines, and measurable impact. • Partner with Procurement, Finance, Commercial Operations, and brand teams to improve working/non-working media efficiency, strengthen scope discipline, and ensure media fees, pass-throughs, invoices, accruals, and reconciliations are managed appropriately. • Establish consistent planning principles, operating rhythms, decision forums, documentation standards, and performance review processes across the portfolio while allowing for brand-specific needs and market conditions. • Collaborate with internal teams, including Brand Marketing, Digital & Analytics, Business Operations, CRM, Privacy, and Compliance stakeholders to ensure media plans are integrated with omnichannel roadmaps and customer engagement capabilities. • Define measurement frameworks, KPIs, dashboards, reporting inputs, and learning agendas in partnership with agency, analytics and digital teams, ensuring measurement goes beyond activity metrics to assess business impact. Identify optimization opportunities and recommend action. • Champion a test-and-learn culture by identifying emerging channels, innovative media partnerships, AI-enabled media opportunities, audience refinement approaches, creative testing, and measurement pilots that can improve customer relevance and business impact. • Bring forward portfolio-level learnings and best practices that can be transferred across brands to improve efficiency, consistency, capability building, and commercial impact. • Influence senior stakeholders through structured recommendations, clear storytelling, strong strategic judgment, and evidence-based decision-making. • Perform other duties as assigned. Leadership Responsibility This is a senior individual contributor role that leads through media expertise, business partnership, and influence across a highly matrixed organization. The Director will coordinate