Senior Legal Counsel, Clinical

• Draft, review, negotiate and execute a wide variety of clinical research agreements, including Clinical Trial Agreements (CTA), Master Service Agreements (MSA), investigator agreements, site contracts, laboratory service agreements, clinical supply agreements and patient and subject-related agreements. • Serve as the primary, day-to-day legal business partner embedded directly alongside the Clinical Development team. • Partner with internal stakeholders to establish, scale and optimise standardised clinical contracting playbooks and template libraries to streamline study start-up timelines. • Identify, manage and mitigate legal, regulatory, intellectual property, data privacy, and compliance risks across global clinical operations. • Collaborate closely with cross-functional Legal & Business Operations colleagues (IP, Corporate Legal and Privacy) to ensure end-to-end alignment on trial governance and data rights. • Manage outside counsel and clinical transactions legal budget. • Proactively evaluate, pilot, and embed cutting-edge AI technologies into the clinical contracting lifecycle to accelerate legal operations.

• J.D. or equivalent law degree with active U.S. state bar admission in good standing (Massachusetts Bar or eligible for in-house registration in MA). • Substantial, direct experience structuring, drafting, and negotiating complex clinical trial agreements, Master Service Agreements (MSA), investigator agreements, site contracts, laboratory service agreements, clinical supply agreements and patient and subject-related agreements. • Experience gained either within a biotechnology/pharmaceutical in-house legal department or a specialised life sciences law firm practice. • Expert knowledge of clinical trial execution, CRO outsourcing models and regulatory guidelines (GCP/ICH). • Proven ability to work autonomously and prioritise a high volume of transactions in a fast-paced, high-growth environment. • Strong collaborative mindset with exceptional stakeholder communication skills, tailored to embedding directly with scientific, medical and clinical operations teams. • Familiarity with global and multi-jurisdictional clinical trial contracting landscapes (US, UK, and EU regulatory frameworks). • Experience navigating clinical data rights and IP provisions at the intersection of computational biology, data-intensive research, or AI-driven platforms.

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease. The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery. Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture. The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you. About Iso Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed. Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases. We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design. Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI. As Senior Legal, Clinical, you will play a pivotal role in advancing our drug candidates into and through clinical development. Working as part of our global legal function, and embedded directly alongside our clinical operations and development teams in Cambridge, you will serve as the dedicated legal partner driving the drafting, negotiation and execution of high-volume, critical clinical research agreements. Your expertise will safeguard IsoLabs' intellectual property and regulatory posture, while accelerating clinical trial initiation, directly contributing to our mission of bringing AI-designed medicines to patients at digital speed. What you will do • Draft, review, negotiate and execute a wide variety of clinical research agreements, including Clinical Trial Agreements (CTA), Master Service Agreements (MSA), investigator agreements, site contracts, laboratory service agreements, clinical supply agreements and patient and subject-related agreements. • Serve as the primary, day-to-day legal business partner embedded directly alongside the Clinical Development team. • Partner with internal stakeholders to establish, scale and optimise standardised clinical contracting playbooks and template libraries to streamline study start-up timelines. • Identify, manage and mitigate legal, regulatory, intellectual property, data privacy, and compliance risks across global clinical operations. • Collaborate closely with cross-functional Legal & Business Operations colleagues (IP, Corporate Legal and Privacy) to ensure end-to-end alignment on trial governance and data rights. • Manage outside counsel and clinical transactions legal budget. • Proactively evaluate, pilot, and embed cutting-edge AI technologies into the clinical contracting lifecycle to accelerate legal operations. Skills and qualifications • J.D. or equivalent law degree with active U.S. state bar admission in good standing (Massachusetts Bar or eligible for in-house registration in MA). • Substantial, direct experience structuring, drafting, and negotiating complex clinical trial agreements, Master Service Agreements (MSA), investigator agreements, site contracts, laboratory service agreements, clinical supply agreements and patient and subject-related agreements. • Experience gained either within a biotechnology/pharmaceutical in-house legal department or a specialised life sciences law firm practice. • Expert knowledge of clinical trial execution, CRO outsourcing models and regulatory guidelines (GCP/ICH). • Proven ability to work autonomously and prioritise a high volume of transactions in a fast-paced, high-growth environment. • Strong collaborative mindset with exceptional stakeholder communication skills, tailored to embedding directly with scientific, medical and clinical operations teams. • Familiarity with global and multi-jurisdictional clinical trial contracting landscapes (US, UK, and EU regulatory frameworks). • Experience navigating clinical data rights and IP provisions at the intersection of computational biology, data-intensive research, or AI-driven platforms. Culture and values We are guided by our shared values. It's not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it. Thoughtful Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day. Brave Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less. Determined Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we. Together Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere. Creating an extraordinary company